Why is Vitamin K important?
An abundance of human clinical data reveals that vitamin K plays a critical role in maintaining healthy bone density by facilitating the transport of calcium from the bloodstream into the bone. Vitamin K is also required by calcium-regulating proteins in the arteries. Matrix Gla-protein (MGP) is a vitamin K-dependent protein, and it must be carboxylated to function properly. Poor vitamin K status leads to inactive uncarboxylated MGP (ucMGP), which accumulates at sites of arterial calcification. Since MGP is a potent local inhibitor of arterial calcification, MGP is important in relation to the health of the entire cardiovascular system. Without adequate vitamin K, calcium in the blood can bind to the arterial wall resulting in calcification. As people age, even a subclinical vitamin K deficiency can pose risks to the vascular system. Poor vitamin K status also results in increased circulating levels of undercarboxylated osteocalcin that is shown to be associated with increased bone loss in postmenopausal women.
Humans get most of their vitamin K from green vegetables in the form of vitamin K1. The problem is that K1 is tightly bound to plant fiber and only a small fraction absorbs into the bloodstream.
In recent years, two forms of vitamin K2 have been extensively researched and the findings reveal vastly improved effects compared to K1. The MK-4 form of vitamin K2 is the most rapidly absorbed and is now routinely used in Japan to maintain healthy bone density. MK-4, however, only remains active in the blood for a few hours. The MK-7 form of K2, on the other hand, remains bioavailable to the human body over a sustained 24-hour period24 and to higher levels (seven- to eightfold) during prolonged intake. Both MK-4 and MK-7 have demonstrated remarkable health benefits when studied in human populations.
Directions: Take one softgel daily with food, or as recommended by a healthcare practitioner.
Caution: If you are taking anti-coagulant or anti-platelet medication, or have a bleeding disorder, consult with your healthcare provider before taking this product.
| Supplement Facts: |
Amount per serving: |
| Serving size: 1 Softgel |
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| Servings per container: 90 |
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Vitamin C (as Ascorbyl palmitate)
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10 mg |
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Vitamin K activity
From:
Vitamin K1 (as phytonadione)
Vitamin K2 (as menaquinone-4)
Vitamin K2 (as menaquinone-7)
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2600 mcg
1500 mcg
1000 mcg
100 mcg
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| |
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Other ingredients: extra virgin olive oil, gelatin, glycerin, beeswax, purified water, carob color, mycrocrystalline cellulose maltodextrin.
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
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